it also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing somatostatin release | |
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it acts on the "sulfonylurea receptors" on pancreatic? it also exerts extrapancreatic action- by sensitizing the target tissues such as liver to insulin action | it primarily increases 2nd phase insulin secretion and has little effect on 1st phase |
it increases the number of insulin receptors and through a post receptor action improving translation of receptor activation.
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