Most laboratories and clinicians are unaware of macroprolactin interferences in prolactin assays | Galactor-rhea was present in 81 |
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1 Estradiol — 127 Progestrone — 2 | However, in some cases the high levels of PRL cannot be explained even after an extensive clinical, hormonal and neuro-radiological work-up |
A speculation on the source of these antibodies suggests that posttranslational modifications glycosylation and phosphorylation of some proteins may create neo-epitopes for the production of autoantibodies ,.
5Thereafter, several cases of macroprolactinemia have been reported | 00 Postmenopausal not on HRT :5 |
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-RH B RH POSITIVE COOMBS INDIRECT NEGATIVE HBS ANTIGEN SURFACE AG | 7 Estradiol 223 Progesterone 1 |
also demonstrated the pre-dominance of the highest molecular weight prolactin in a woman complaining of infertility who conceived subsequently.
16